Table 2 Effects of orally administered bisphenol A (BPA), isosorbide (ISO) and cyclohexanedimethanol (CHDM) and subcutaneously administered testosterone propionate (TP) on androgen-insensitive organ weights of castrated rats

Treatment^a	Kidney(mg)	Spleen(mg)	Liver(g)
INT	1,117.8±17.1	696.1±33.7	11.0±0.4
ORX	1,063.9±16.1	688.1±34.1	11.3±0.5
ORX+TP	1,098.3±18.1	895.4±55.8	12.2±0.4
BPA-40	879.7±9.5^***	634.0±25.6	9.2±0.3^**
BPA-40+TP	1,006.4±15.6^†††	746.6±59.1	11.0±5.2
BPA-400	935.6±25.3^***	625.3±43.2	10.1±0.4
BPA-400+TP	1,044.2±17.7^†	629.0±20.7^††	10.9±0.3^†
ISO-40	1,045.5±18.9	803.9±71.6	10.2±0.2
ISO-40+TP	1,092.7±22.7	720.5±21.1†	10.8±0.4^†
ISO-400	1,038.1±26.7	744.6±31.5	11.2±0.5
ISO-400+TP	1,111.4±29.5	794.2±48.3	11.8±0.4
CHDM-40	965.6±21.2^**	666.8±28.0	10.1±0.3
CHDM-40+TP	1,117.7±14.5	761.6±38.2	12.3±0.3
CHDM-400	1,036.0±38.7	706.2±33.7	11.0±0.4
CHDM-400+TP	1,164.0±20.9^†	789.6±47.9	12.4±0.4

^a Castrated immature rats were administered with TP by subcutaneous injection for 10 days. One day after the final treatment, the accessory sex organs were removed carefully and weighed separately.
Symbols ^{*, **} and ^***meant significant difference in comparison between ORX group and test material group. ^*, P<0.05; ^**, P<0.01; ^***, P<0.001.
Symbols ^+, ⁺⁺ and ⁺⁺⁺ meant significant difference in comparison between ORX group and test material group.^†, P<0.05; ^††, P<0.01; ^†††, P<0.001.